Genetically modified mice open the door to personalized medicine in rare diseases

An international research team led by Dr. Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, CSIC-UAM joint center) in which the Complutense University of Madrid (UCM) participates introduced into mice -through CRISPR gene editing techniques–, mutation of the protein MCT8, responsible for the transport of thyroid hormones into the interior of the cell. … Read more

They reveal how the body optimizes respiratory capacity during exercise

Mitochondria are multifunctional organelles whose dysfunction is associated with cardiovascular, inflammatory or neurodegenerative diseases and the aging process. They are the main powerhouses of cells and produce most of their energy from basic compounds such as sugars or lipids in a process known as mitochondrial respiration. One of the main causes of cell damage in … Read more